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SOLUTIONS
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BUILT-IN MATHEMATICA SYMBOL
CoxModelFit
CoxModelFit[{e1, ..., en}]
constructs a model of the baseline hazard
for events times
.
CoxModelFit[{{{
11, ...,
1p}, ..., {
n1, ...,
np}}, {e1, ..., en}}, {f1, ..., fm}, {x1, ..., xp}]
constructs a Cox model of the form
, where the
depend on the
.
Details and OptionsDetails and Options
- CoxModelFit is used in survival, reliability, and duration analysis. It quantifies relative survival risk and estimates an underlying baseline hazard.
- CoxModelFit returns a symbolic CoxModel object to represent the proportional hazards model it constructs. The properties and diagnostics of the model can be obtained from model["property"].
- A list of available model properties can be obtained using model["Properties"].
- The form of events
follows the form used in EventData. - CoxModelFit produces a conditional hazard function
proportional to the baseline hazard function
. - The model is semiparametric, with parameters
found by maximizing a partial likelihood. The baseline hazard
is estimated using nonparametric methods. - A null model that only estimates
can be specified using CoxModelFit[e], which is equivalent to CoxModelFit[{
, e}, {}, {x1, ..., xp}]. - Constant values specified in the basis functions
are ignored in the fitting and absorbed in the estimation of the baseline hazard
. - The following tables of properties pertain to the estimates, diagnostics, and testing of the parametric components
of the model. - Properties related to data and the fitted function obtained using model["property"] include:
-
"BaselineList" list containing baseline covariate levels for each stratum "BasisFunctions" list of basis functions 
"BestFitParameters" parameter estimates 
"Data" the matrix of covariate input data 
"EventData" the event input data 
"RelativeRisk" relative risk
for the model parameters"StrataModels" list containing submodels for each stratum "StrataSummary" list containing name and count pairings for each stratum - Properties that measure goodness of fit include:
-
"AIC" Akaike information criterion "BIC" Schwartz-Bayes information criterion "LogLikelihood" model log likelihood "MaxRSquared" maximum possible
coefficient"RSquared" pseudo coefficient of determination 
- Types of residuals and influence measures:
-
"BetaDifferences" DFBETAs measure of influence on parameter values "CoxSnellResiduals" Cox-Snell type residuals "DevianceResiduals" scaled Martingale residuals "MartingaleResiduals" estimate of the excess number of events over time "ScaledBetaDifferences" DFBETAs computed using the model standard deviation "SchoenfeldResiduals" Schoenfeld-type residuals "ScoreResiduals" score residuals - Properties and diagnostics for parameter estimates include:
-
"CovarianceMatrix" covariance estimate for model parameters "InformationMatrix" information matrix for model parameters "LikelihoodRatioStatistic" likelihood ratio of fitted model to the null model "ParameterConfidenceIntervals" confidence intervals about the parameter estimates "ParameterStandardErrors" standard errors of model parameters "ParameterTable" table of fitted parameter information "ParameterTableEntries" entries in the parameter table "RelativeRiskConfidenceIntervals" confidence intervals about relative risk estimates "RiskScores" risk scores for each observation "ScoreStatistic" score statistic comparing fitted and null models "TestTable" table of signficance information for model parameters "TestTableEntries" entries from the test table "TestTableEntriesFunction" entries from table created with test table function "TestTableFunction" creates a test table under a specified null hypothesis "WaldStatistic" Wald statistic comparing fitted and null models - As in SurvivalModelFit, it is possible to obtain information about the nonparametric component of the model
, including estimates of survival probabilities, survival confidence intervals, and moment estimates. - CoxModelFit has all of the properties available to SurvivalModelFit.
- Properties related to
are specified as in SurvivalModelFit, but additionally require that the covariate level
be given as
. - Different functional forms of the hazard rate
for covariate levels
can be obtained by specifying the form h in
. The following forms can be used. -
"CDF" cumulative distribution function "CHF" cumulative hazard function "SF" survival function - The value of the fitted function h from CoxModelFit at a particular point t and covariate levels
can be found from
.
gives the form h of the baseline hazard
. - Specifying Normal[model] gives a pure function form of
. - CoxModelFit takes the following options:
-
ConfidenceLevel 95/100 level to use for intervals and bands ConfidenceRange All range for simultaneous confidence bands ConfidenceTransform "LogLog" confidence transform to use Method Automatic method to use for model fitting NominalVariables None variables considered as categorical StrataVariables None variables considered as strata WorkingPrecision Automatic precision used in internal computations - With ConfidenceLevel->p, probability-p confidence intervals and bands are computed for the various functional forms and parameter estimates.
- ConfidenceRange->{tmin, tmax} gives probability-p simultaneous confidence intervals and bands for the fitted function between
and
. - Possible settings for ConfidenceTransform include
,
,
,
,
, or a pure function g. - The setting Method->m specifies the method for handling ties. Possible settings include the following.
-
"Breslow" use Breslow's partial likelihood "Efron" use Efron's partial likelihood "Exact" use the exact marginal likelihood - By default, the
method is used for handling ties. - Additional method settings can be found in the options section of examples.
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