Apply an autoionization reaction to water:

Apply a reaction between an organic acid and base:

Apply the same reaction with the reactants reversed, treating histidine as the acid and alanine as the base:

Apply a reaction to convert an alkene to an alcohol:

Find matching "Chemical" entities for the products:

Create a pattern reaction for the Diels–Alder reaction from a reaction SMARTS string:

Apply the pattern reaction to a diene and a dienophile:

React a radical chlorine atom with methane:

Define a reaction for an intermolecular esterification:

Apply the pattern reaction to a carboxylic acid and an alcohol:

Apply the pattern reaction to a carboxylic acid and an isotopically labeled alcohol:

Define a pattern reaction for an intramolecular esterification:

Form a lactone (cyclic ester) from a hydroxylated carboxylic acid:

Find all possible lactones from a carboxylic acid with multiple hydroxyl groups:

Define a pattern reaction for acetylation:

Acetylate salicylic acid to form aspirin:

Exhaustively acetylate the sugar sucrose:

Synthesize phthalide from o-phthalaldehyde by applying a sequence of reactions:

A pattern reaction representing amide formation for peptides:

Generate molecules corresponding to the standard amino acids:

Generate a peptide from its amino acid sequence:

The result is equivalent to the one obtained from BioSequence:

The result of ApplyReaction depends on the order in which the reactant molecules are supplied:

The benzidine rearrangement is a rearrangement reaction for making biaryl amines:

Use the benzidine rearrangement to make benzidine from hydrazobenzene:

The Ugi reaction is a typical example of a multicomponent reaction. Here is a three-component version:

Various local anesthetics can be synthesized using the Ugi reaction, depending on the starting materials used:

These correspond to the anesthetics lidocaine and prilocaine: