WOLFRAM SYSTEM MODELER

InsulinSignaling

A model of insulin receptor and insulin receptor substrate 1 phosphorylation (Brännmark et al., 2010)

Package Contents

MainModel

Main model of the example

CustomReactions

Package with custom reactions

Information

Insulin signaling in human adipocytes.

This example is a slightly modified version of the final model published by C. Brännmark et al (2010).

See also

The MainModel model for further documentation and simulation results.

References

C. Brännmark, R. Palmér, S. T. Glad, G. Cedersund, and P. Strålfors, "Mass and Information Feedbacks through Receptor Endocytosis Govern Insulin Signaling as Revealed Using a Parameter-Free Modeling Framework," Journal of Biological Chemistry, 285(26), 2010, pp. 20171-20179 doi:10.1074/jbc.M110.106849

Wolfram Language

In[1]:=
SystemModel["BioChem.Examples.InsulinSignaling"]
Out[1]:=