The Wolfram Language's symbolic representation of both graphics and controls makes it particularly easy to create click-interactive panels in which the user clicks or drags elements embedded in a fixed overall image.

Manipulate — create a simple panel containing Locator objects

Dynamic — set up dynamic variables and a dynamic overall display

DynamicModule — localize and save dynamic variables

LocatorPane — place one or more locators with arbitrary appearances on any image

LocatorAutoCreate — option to allow new locators to be created by clicking

Locator — set up a movable thumb connected to a dynamic variable

ClickPane — respond to the locations of clicks on any image, perhaps dynamic

Layout & Annotation

Panel  ▪  TabView  ▪  Mouseover  ▪  Tooltip  ▪  EmitSound

Graphics Construction »

Graphics  ▪  Point  ▪  Line  ▪  Polygon  ▪  Disk  ▪  ...

PlotRange — specify a fixed coordinate system

Lower-Level Control »

EventHandler  ▪  MousePosition  ▪  CurrentValue  ▪  ControllerState  ▪  ...